1-N-BOC-3-(4-BROMOBENZYL) PIPERIDINE-3-CARBOXYLIC ACID
1-n-boc-3-(4-bromobenzyl) piperidine-3-carboxylic acid
CAS: 959235-99-5
Molecular Formula: C18H24BrNO4
1-N-BOC-3-(4-BROMOBENZYL) PIPERIDINE-3-CARBOXYLIC ACID - Names and Identifiers
1-N-BOC-3-(4-BROMOBENZYL) PIPERIDINE-3-CARBOXYLIC ACID - Physico-chemical Properties
| Molecular Formula | C18H24BrNO4 |
| Molar Mass | 398.29 |
1-N-BOC-3-(4-BROMOBENZYL) PIPERIDINE-3-CARBOXYLIC ACID - Introduction
1-n-boc-3-(4-bromobenzyl) piperidine-3-carboxylic acid is an organic compound with the chemical formula C20H26BrNO4 and a molecular weight of 414.33g/mol.
The compound is a white or slightly yellow crystal with a high melting point. It is stable at room temperature and relatively stable under dry conditions.
1-n-boc-3-(4-bromobenzyl) piperidine-3-carboxylic acid has a wide range of applications in the field of organic synthesis. It is an intermediate in the preparation of drugs and biologically active molecules. It can be used as a protecting group for 3-piperidinecarboxylic acid in order to protect it during the synthesis and avoid reactions at sites where activity is not desired. In addition, it can also be used for the synthesis of compounds with biological activity on the phosphocreatine alcohol kinase inhibitors.
The method for preparing 1-n-boc-3-(4-bromobenzyl) piperidine-3-carboxylic acid is relatively complicated, mainly including multi-step reactions. The usual synthesis is the reaction of 3-piperidinecarboxylic acid with p-bromobenzyl alcohol followed by a transesterification reaction with 1-tert-butyloxycarbonyl-3-piperidinecarboxylate in methanol.
Use safety precautions when using 1-n-boc-3-(4-bromobenzyl) piperidine-3-carboxylic acid. Compounds may be toxic and irritating to humans and direct contact with skin, eyes and mouth should be avoided. Appropriate protective equipment such as gloves, safety glasses and laboratory coats should be worn during operation. In addition, the compound should be stored properly, avoiding contact with oxygen, moisture and strong acids to prevent its degradation and failure.
The compound is a white or slightly yellow crystal with a high melting point. It is stable at room temperature and relatively stable under dry conditions.
1-n-boc-3-(4-bromobenzyl) piperidine-3-carboxylic acid has a wide range of applications in the field of organic synthesis. It is an intermediate in the preparation of drugs and biologically active molecules. It can be used as a protecting group for 3-piperidinecarboxylic acid in order to protect it during the synthesis and avoid reactions at sites where activity is not desired. In addition, it can also be used for the synthesis of compounds with biological activity on the phosphocreatine alcohol kinase inhibitors.
The method for preparing 1-n-boc-3-(4-bromobenzyl) piperidine-3-carboxylic acid is relatively complicated, mainly including multi-step reactions. The usual synthesis is the reaction of 3-piperidinecarboxylic acid with p-bromobenzyl alcohol followed by a transesterification reaction with 1-tert-butyloxycarbonyl-3-piperidinecarboxylate in methanol.
Use safety precautions when using 1-n-boc-3-(4-bromobenzyl) piperidine-3-carboxylic acid. Compounds may be toxic and irritating to humans and direct contact with skin, eyes and mouth should be avoided. Appropriate protective equipment such as gloves, safety glasses and laboratory coats should be worn during operation. In addition, the compound should be stored properly, avoiding contact with oxygen, moisture and strong acids to prevent its degradation and failure.
Last Update：2024-04-09 20:52:54
